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Welcome to the
Ordonez-Rubiano Lab at
Georgia Southern University!

Unraveling transcriptional regulators in cancer.

Dr. Sandra Carolina Ordonez-Rubiano
Principal Investigator

Meet Dr. Sandra C. Ordonez-Rubiano

I lead the Ordonez-Rubiano Lab at Georgia Southern University, where we use novel chemical tools to unravel transcriptional regulators in cancer. My passion for cancer research was sparked during clinical rotations at Colombia’s National Cancer Institute, and I developed a strong commitment to mentorship throughout my PhD at Purdue University and postdoctoral training at Stanford University. As a principal investigator, my goal is to advance the development of anticancer treatments while supporting my trainees through a holistic approach.

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Student opportunities

We are looking for motivated graduate and undergraduate researchers to join the lab. If you are curious about chemical biology and how it can be applied to answer questions in the cancer biology field, we want to hear from you.

Graduate and undergraduate students welcomeResearch projects at the interface of chemical biology, drug discovery and cancer researchStudent-centered mentoring approach

Research

We work at the interface of chemistry and biology to enhance our understanding of the role transcriptional regulators play in cancer and their potential as therapeutic targets.

Brain Sciences · 2025

Current Applications of Single-Cell RNA Sequencing in Glioblastoma: A Scoping Review

Ordóñez-Rubiano, E.; Rincón-Arias, N; Shelton, W.; Salazar, A.; Sierra, M.; Bertani, R.; Gómez-Amarillo, D.; Hakim, F.; Baldoncini, M.; Payán-Gómez, C.; Cómbita, A.; Ordonez-Rubiano, S.; Parra-Medina, R.
Frontiers in Epigenetics and Epigenomics · 2024

SWI/SNF chromatin remodelers in prostate cancer progression

Ordonez-Rubiano, S.; Strohmier, B.; Sood, S.; Dykhuizen, E.
Journal of Medicinal Chemistry · 2023

Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer

Ordonez-Rubiano, S.; Maschinot, C.; Wang, S.; Sood, S.; Strohmier, B.; McQuade, A.; Smith, B.; Dykhuizen, E.
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