Selected work

Publications

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ReviewManuscript in preparation

The role of SWI/SNF chromatin remodelers during different stages of prostate cancer progression

Ordonez-Rubiano, S.; Strohmier, B.; Sood, S.; Dykhuizen, E.
TitleThe role of SWI/SNF chromatin remodelers during different stages of prostate cancer progression
AuthorsOrdonez-Rubiano, S.; Strohmier, B.; Sood, S.; Dykhuizen, E.
StatusManuscript in preparation
ArticleJournal of Medicinal Chemistry · 2023

Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer

Ordonez-Rubiano, S.; Maschinot, C.; Wang, S.; Sood, S.; Strohmier, B.; McQuade, A.; Smith, B.; Dykhuizen, E.
TitleRational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
AuthorsOrdonez-Rubiano, S.; Maschinot, C.; Wang, S.; Sood, S.; Strohmier, B.; McQuade, A.; Smith, B.; Dykhuizen, E.
Year2023
DOI10.1021/acs.jmedchem.3c00671
ArticleJournal of Medicinal Chemistry · 2022

Selective and cell-active PBRM1 bromodomain inhibitors discovered through NMR fragment screening

Shishodia, S.; Nuñez, R.; Strohmier, B.; Bursch, K.; Goetz, C.; Olp, M.; Jensen, D.; Kenske, T.; Ordonez-Rubiano, S.; Blau, M.; Roach, M.; Peterson, F.; Volkman, B.; Dykhuizen, E.; Smith, B.
TitleSelective and cell-active PBRM1 bromodomain inhibitors discovered through NMR fragment screening
AuthorsShishodia, S.; Nuñez, R.; Strohmier, B.; Bursch, K.; Goetz, C.; Olp, M.; Jensen, D.; Kenske, T.; Ordonez-Rubiano, S.; Blau, M.; Roach, M.; Peterson, F.; Volkman, B.; Dykhuizen, E.; Smith, B.
Year2022
DOI10.1021/acs.jmedchem.2c00864
ArticleThe FASEB Journal · 2022

Design and Synthesis of Bi-Aryl Methylated Lactam Derivatives to Inhibit the BRD7 Bromodomain Function in Prostate Cancer

Ordonez-Rubiano, S.; Maschinot, C.; Dykhuizen, E.
TitleDesign and Synthesis of Bi-Aryl Methylated Lactam Derivatives to Inhibit the BRD7 Bromodomain Function in Prostate Cancer
AuthorsOrdonez-Rubiano, S.; Maschinot, C.; Dykhuizen, E.
Year2022
DOI10.1096/fasebj.2022.36.S1.R2058
ReviewNAR Cancer · 2021

Polycomb Group Proteins in Cancer: Multifaceted Functions and Strategies for Modulation

Wang, S.; Ordonez-Rubiano, S.; Dhiman, A.; Jiao, G.; Strohmier, B.; Krusemark, C.; Dykhuizen, E.
TitlePolycomb Group Proteins in Cancer: Multifaceted Functions and Strategies for Modulation
AuthorsWang, S.; Ordonez-Rubiano, S.; Dhiman, A.; Jiao, G.; Strohmier, B.; Krusemark, C.; Dykhuizen, E.
Year2021
DOI10.1093/narcan/zcab039
ArticleChemBioChem · 2021

A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation

Wang, S.; Alpsoy, A.; Sood, S.; Ordonez-Rubiano, S.; Dhiman, A.; Sun, Y.; Jiao, G.; Krusemark, C.; Dykhuizen, E.
TitleA Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation
AuthorsWang, S.; Alpsoy, A.; Sood, S.; Ordonez-Rubiano, S.; Dhiman, A.; Sun, Y.; Jiao, G.; Krusemark, C.; Dykhuizen, E.
Year2021
DOI10.1002/cbic.202100118
ArticleRevista Colombiana de Ciencias Químico-Farmacéuticas · 2017

Design and synthesis of isatinic and spiro compounds as potential anticancer agents

Ordonez-Rubiano, S.; Orozco, F.
TitleDesign and synthesis of isatinic and spiro compounds as potential anticancer agents
AuthorsOrdonez-Rubiano, S.; Orozco, F.
Year2017
VenueRevista Colombiana de Ciencias Químico-Farmacéuticas